Edit, 3/28/18: RStudio just announced Python interoperability through the reticulate package. Rmd Notebooks are unbeatable, in my opinion.
Original Post: I started using Jupyter Notebooks back when they were called IPython. I even remember having to set up a virtual Linux environment because they were not available on Windows. As much as I have enjoyed their functionality, I recently switched entirely to R Markdown in an RStudio environment. Here’s why.